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What is Polyglutamic Acid in Skincare?

If you haven’t heard of polyglutamic acid before, you aren’t behind the times. This ultra-hydrating skin plumper has been largely overlooked as its moisture-binding sister molecule, hyaluronic acid, has achieved cult status.It’s time to give polyglutamic acid’s skin-flooding superpowers the recognition they deserve. Join us as we dive deep into the science behind polyglutamic acid’s powerful skincare benefits and explain how to use it in your routine.

What is Polyglutamic Acid?

Polyglutamic acid is a fermented ingredient formed when multiple molecules of glutamic acid are linked together via the fermentation process to form a natural, biodegradable polymer. Polyglutamic acid (PGA) is also a peptide that can easily penetrate the top layers of skin to support collagen production.

Polyglutamic acid attracts water from the surrounding environment and pulls it into your skin. As a polymer, it also forms a protective skin to keep it evaporating, locking moisture into your skin.

Why is PGA Used in Skincare?

As we age, our skin begins losing its natural hydrator, hyaluronic acid, as it’s broken down by an enzyme called hyaluronidase. Polyglutamic acid serums – such as our Copper Peptide Rapid Plumping Serum – inhibit the action of hyaluronidase, preserving hyaluronic acid in the skin while also flooding the skin with additional moistureCopper Peptides Ingredient on Spoon

6 Skincare Benefits of Polyglutamic Acid:

  • Hydrates skin
  • Locks in moisture
  • Reduces the appearance of fine lines and wrinkles
  • Improves the appearance of enlarged pores
  • Boosts Elasticity
  • Replenishes cell moisture


 Polyglutamic Acid vs. Hyaluronic Acid

Hyaluronic acid (HA)  achieved its well-deserved cult status as a non-irritating hydrator for its ability to bind with water and pull it into the skin. While PGA also binds with water, its larger molecular size enables it to hold five times more moisture than HA. Those bigger molecules also weigh more, allowing it to dramatically smooth the top layers of the skin. PGA’s final party trick: it seals in the moisture it attracts, flooding the skin with hydration and holding it there for a lasting plumping effect. All of these powerful anti-aging benefits aside, we like to think of polyglutamic acid and hyaluronic acid as friends, not competitors. These two ingredients work beautifully when combined to double down on skin-smoothing hydration.

About Our Polyglutamic Acid Serum

Our award-winning Copper Peptide Rapid Plumping Serum combines the ultra-hydrating power of PGA with hyaluronic acid and ectoin to flood skin with moisture and seal it in for continuous, lasting hydration. Meanwhile copper peptides support collagen and elastin for bouncy skin and boost production of hyaluronic acid for even more hydration in a unique symbiosis of ingredients for ultimate results.

In consumer trials, 97 percent of participants reported a visible firmness in smoothness and elasticity. Even better, 100 percent noticed visible improvement in fine lines and wrinkles after 4 weeks of use.Copper Peptide Rapid Plumping Serum with blue serum spilling out

How to Use Polyglutamic Acid in Your Skincare Routine

Polyglutamic acid’s moisture-binding abilities make it  an ideal ingredient for people with dry, dehydrated, or stressed-out skin. It also works harmoniously with skincare actives including retinol and vitamin C

We recommend applying a polyglutamic acid serum such as our Copper Peptide Rapid Plumping Serum while skin is still damp from toning. This allows the PGA to bind with the water molecules sitting on top of your skin, pulling them into your epidermis and boosting PGA’s hydrating, plumping effect. 

Try this routine for integrating polyglutamic acid into your skincare regimen:

Step One:Amino Aloe Gentle Cleanser - Lather this gel cleanser into a satisfying foam to deep clean pores without over-stripping. Amino acids dissolve dirt and makeup while aloe soothes and sugarcane-derived squalane delivers a burst of hydration. 

Step Two: Hyaluronic Acid Facial Mist - Balance your skin with a refreshing spritz of our hydrating facial mist to plump and prep skin for the rest of your routine.

Step Three: Copper Peptide Rapid Plumping Serum - Massage a dropper full of this luxurious, silky serum into your face as the third step in your skincare routine to instantly plump fine lines and wrinkles with the power of PGA, HA, ectoin, and elasticity-boosting copper peptides.

Step Four: Vitamin C Rose Moisturizer- Follow serum with our first-of-its-kind moisturizer for an instant brightening and moisture. Squalane effectively delivers a powerful boost of hard-working antioxidants with strong brightening capabilities into the skin, in order to fight free radicals and pollution, leaving the skin more radiant and smooth.

Step Five: Vitamin C Rose Oil- Lock in moisture and create a lit-from-within glow with our cult-favorite facial oil. Our oil-soluble, shelf-stable Vitamin C hydrates and brightens, while our superhero squalane drives your skincare deeper into your skin for enhanced efficacy.

Christine Tusher
Christine Tusher Writer and expert
As a lifestyle writer and journalist, I love sharing my passion for ocean conservation and obsession with clean beauty. I’ve tried almost every trend and ingredient, and Biossance’s science-backed formulas are the only ones that consistently calm my reactive skin and make it smoother, clearer, and healthier. I’m so excited to be on this journey of skincare innovation with Biossance, and to share it with you!

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